HIGH TSH - HIGH THYREOTROPIN symptoms and causes


A High TSH it is almost always indicative of hypothyroidism. The causes and symptoms of high TSH are explained in this article. The TSH (thyrotropin or thyrotropic hormone) is a substance produced by the anterior part of the pituitary gland, the adenohypophysis. It is the fundamental hormone that regulates the functionality and efficiency of the thyroid, which is stimulated to produce thyroid hormones (T3 or triiodothyronine and T4 or thyroxine) starting from the precursor molecule thyroglobulin. The measurement of thyroid hormones during blood tests is carried out on the free fraction of these hormones, which in turn reflects the total amount of T3 and T4 present in the circulation. It is therefore more correct to refer to thyroid hormones with the terminology fT3 (free T3) and fT4 (free T4).

High TSH values

The TSH is high when it exceeds 4 mIU / L.

TSH: when to take the exam

The TSH it is dosed to evaluate thyroid function and identify any alterations both in the sense of hyperactivity of the thyroid gland (hyperthyroidism) and in case of hypofunction (hypothyroidism); measuring TSH also serves to monitor the effectiveness of therapeutic treatment in case of hypothyroidism (monitoring of thyroid hormone replacement therapy) or hyperthyroidism (monitoring of thyroid suppressive therapy).

Not infrequently we find the indication in the doctor's prescriptions or in blood tests TSH reflex or TSH reflex: it is good to clarify that this wording does not indicate a particular type of TSH, but simply indicates to the laboratory that a protocol can be implemented that helps to optimize medical costs: therefore, only the TSH is measured first and then, if the value of the latter it is altered, we continue with the dosage, on the same blood sample, of the thyroid hormones. Hence TSH reflex and TSH both indicate thyrotropin hormone.

High TSH

TSH above normal is associated with a number of medical conditions: in case of high TSH it is always necessary to measure at least one of the two types of thyroid hormones, fT3 or fT4. This allows us to understand if, as happens in most cases, there is a reduced function of the thyroid, ie a hypothyroidism, or if, less frequently, there is a hyperfunction of the thyroid, and therefore a hyperthyroidism. 

High TSH causes

A High TSH it can be found both in response to a reduced production of thyroid hormones by the thyroid gland (condition of hypothyroidism), either in the presence of an increased production of TSH, at the pituitary level or in other sites (condition of hyperthyroidism). However, it must be said that in the vast majority of cases the High TSH goes with normal or low fT3 and fT4. 

Below we will explain what are the main causes of high TSH and differentiate those that lead to a condition of hyperthyroidism (TSH high fT3 fT4 high), from those, more frequent, that lead to a condition of hypothyroidism, initially subclinical (High TSH fT3 normal fT4) and then overt hypothyroidism (TSH high fT3 fT4 low).

High TSH and normal fT3 fT4: subclinical hypothyroidism

Hypothyroidism it is a disease characterized by a reduced function of the thyroid gland, which therefore produces the thyroid hormones fT3 and fT4 in insufficient quantities. To compensate for this deficiency, the pituitary gland produces greater quantities of TSH, which will therefore be elevated in blood tests. Initially, the increase in thyrotropin production will be enough to stimulate the thyroid more, obtaining a normalization of thyroid hormone levels. At this stage, said subclinical hypothyroidism, blood tests will result High TSH with normal fT3 and fT4.

High TSH and low fT3 fT4: hypothyroidism

When you are in a more advanced stage, the increased levels of TSH will no longer be enough to maintain normal levels of the hormones produced and secreted by the thyroid. In this situation we speak of real or hypothyroidism overt hypothyroidism, and on blood tests we will have high TSH and low values of fT3 and fT4. Often hypothyroidism, if neglected, leads to the formation of thyroid goiter, that is the enlargement of the thyroid gland linked to a continuous stimulation by TSH.

Here are a few causes of high TSH associated with hypothyroidism:

  • Congenital hypothyroidism: in 85% of cases due to a structural defect of the thyroid gland, as for thethyroid agenesis (lack of formation of the thyroid gland), for the thyroid dysgenesis (abnormal thyroid development), thethyroid ectopia (thyroid in abnormal location compared to the normal anterior pretracheal position) or for thyroid hypoplasia (poorly represented thyroid tissue). In another 10% of cases it concerns a defect in hormone production, which can be linked to a thyroid difficulty concentrate iodine internally due to the presence of a mutation in the iodine / sodium transporter, to a defect of the intrathyroid peroxidase, rather than a defect of the oxidative condensation of MIT and DIT in thyroxine and triiodothyronine, or to a deficiency of desiodation of iodotyrosines, or finally to the production of abnormal iodized compounds which are metabolically hypoactive. All these cases are characterized by Elevated TSH and reduced or absent thyroid hormones.
  • Acute thyroiditis:  the acute thyroiditis they are usually related to bacterial or parasitic infections: in children and adolescents they are often linked to structural thyroid abnormalities such as fistulas in the piriform sinus or residues of the thyroglossal duct in adults they are more often caused by the spread of an infection by proximity of the affected site (infection by contiguity from pharyngitis, tonsillitis, mumps etc.) or by blood dissemination (pulmonary, gastrointestinal, soft tissue infections). The most common symptoms are fever and the appearance of latorecervical adenopathies (swelling and / or pain of the lymph nodes in the neck). The therapy is obviously antibiotic which in most cases causes the thyroiditis to regress and restore normal hormone production by the thyroid.
  • De Quervain's thyroiditis and subacute thyroiditis: the De Quervain's thyroiditis o granulomatous thyroiditis, often occurs following a viral infection, and sometimes requires cortisone therapy. The most common symptoms are fever, asthenia (tiredness), myalgia (muscle aches). It usually resolves with one restitutio ad integrum,  that is, with a return to normal thyroid function. In a 5% of cases, however, a condition of hypothyroidism remains which will require replacement therapy.
  • Hashimoto's thyroiditis e chronic thyroiditis: are the most common forms of thyroiditis, in particular the Hashimoto's thyroiditis it represents by far the most frequent inflammatory thyroid disease (in women 3.5 cases per 1000 people). It is a chronic inflammation of the thyroid gland with autoimmune origin, which leads to chronic damage with residual final hypothyroidism. Symptoms may be absent, or be related to the hypothyroidism that develops in this pathology. Diagnosis is based on the finding of anti-thyroid antibodies: antibodies to thyroperoxidase (anti-TPO) and antibodies to thyroglobulin (anti-TGB), as well as low levels of fT3 and fT4 in the blood. Therapy is essentially replacement with levothyroxine (LT4). Other forms of chronic thyroiditis are the postpartum thyroiditis, the silent tyrolidite and the Riedel's thyroiditis. These inflammatory pathologies are characterized by High TSH, low triiodothyronine and thyroxine and possible presence of anti-thyroid antibodies.
  • Subtotal or total thyroidectomy (partial or complete removal of the thyroid gland): when a part of the thyroid gland is removed, inadequate production of thyroid hormones by the residual gland is generated. This is even more evident with the removal of the entire thyroid, with a total deficiency of hormones. As a compensation mechanism there is an increase in the pituitary production of TSH. The feedback from High TSH after thyroidectomy it is therefore obvious, and is the signal that drug replacement therapy is not yet at optimal doses.
  • Presence of resistance to TSH: resistance to TSH is a pathology that determines a permanent thyroid deficit present at birth. Resistance to TSH is determined by the presence of mutations in the TSH receptor (TSHR; 14q31), which cause a reduced production of thyroid hormones. In this condition then we can find blood tests High TSH and low fT3 fT4.
  • Storage diseases: they are rare pathologies, in which substances that damage the tissues and compromise its function accumulate in the thyroid. As a consequence the production of thorium hormones will be deficient, causing a secondary response at the level of the pituitary gland overproduction of TSH. Among the diseases that deposit in the thyroid we remember hemochromatosis, characterized by iron deposition, and amyloidosis, which causes the deposit of low molecular weight proteins produced in an anomalous and unregulated way by the organism that accumulate between the intracellular spaces of the gland by damaging it.
  • Insufficient thyroid replacement hormone therapy:  it seems obvious but in reality there are many misunderstandings on the subject: patients with a recognized hypothyroidism, who are on thyroid hormone replacement therapy (the most used drug is Eutirox), must carry out periodic blood checks, to regulate therapy. Often the dose of thyroid hormones taken is even slightly insufficient, and this is reflected at the pituitary level with a greater production of thyrotropin, which will be higher than normal. A contrary case, one too high Ft4 dose will tend to lower the levels of thyroid stimulating hormone in the blood. Even with normal thyroid hormones, in the presence of a high TSH it is necessary to consult your doctor or endocrinologist to evaluate whether to slightly modify the dose of thyroid hormones taken daily.

High TSH and high fT3 fT4: hyperthyroidism

Hyperthyroidism is a disease linked to an increased production of thyroid hormones by the thyroid. In the case of a primary hyperthyroidism, in the face of high concentrations of thyroxine and triiodothyronine the pituitary will decrease the production of TSH in order to reduce thyroid activity (low TSH and high thyroxine and triiodothyronine).

In thesecondary hyperthyroidism, it will instead be an excessive production of TSH by the pituitary to stimulate the thyroid in an uncontrolled way: in this situation we will have High TSH and high thyroid hormones. It is this last type of hyperthyroidism which is characterized by high levels of thyrotropin and which we will describe in the next paragraphs.

Here are the causes more frequent than High TSH with hyperthyroidism:

  • Hyperpituitarism (increased pituitary TSH production): it may happen that the pituitary gland produces an abnormal amount of hormones, unregulated with respect to the normal pituitary-target organ control mechanism. Hyperpituitarism can be primitive, if the overproduction of hormones is due to secreting masses such as a pituitary adenoma, or it can be, more rarely, secondary, if the excessive hormone production derives from the lack of negative feedback from the hypothalamus. This occurs in rare cases of hypothalamic secreting tumors (TRH producers in our case). The decisive therapy is the surgical one. This condition is characterized by High TSH and high fT3 and fT4.
  • Ectopic TSH production: paraneoplastic syndrome which determines the production, at the level of non-pituitary neoplasms (lung, breast, uterus, prostate, gastrointestinal), of a substance similar to TSH.

Medicines

There are some drug therapies that can inhibit the secretion of hormones by the gland thyroid, consequently inducing an increase in blood levels of thyrotropin (TSH). Among these the most frequent is amiodarone, an iodine-rich antiarrhythmic drug that can cause both the development of hyperthyroidism but also hypothyroidism. Other common drugs that can generate this side effect are interferon (used in antiviral therapy and in immunohematological therapy), and the lithium, a psychiatric drug used in the treatment of psychiatric conditions such as bipolar disorder or certain types of headache.

Do you want to deepen the topic? We have selected this book that addresses the problem of hypo and hyperthyroidism.

Living without thyroid problems. How to deal with hypo and hyperthyroidism through nutrition, movement, integration

High TSH in pregnancy

Usually the TSH during pregnancy is normal or slightly below the classical reference values: this is because during pregnancy there are some physiological alterations (increase in TBG (Thyroxin Binding Globulin), presence of chorionic gonadotropin) which tend to slightly reduce TSH values.

The finding of a High TSH in pregnancy it must be carefully evaluated, as it can indicate the presence of hypothyroidism, a metabolic state very harmful for the future newborn, since it can compromise the correct somato-neural development. If the thyroid is unable to provide adequate production of T3 and T4, it will be necessary to compensate with supplementary therapy with supportive levothyroxine (Eutirox, Tirosint, etc. ..).

There are particular conditions that must be carefully monitored and which have an increased probability of leading to gestational hypothyroidism. Given that a TSH check before conceiving a child should be done in all cases, the major ones instructions to perform the TSH check during pregnancy are as follows:

  • Over 30 years of age
  • History of family or personal thyroid dysfunction
  • History of previous thyroid surgery.
  • Symptoms of thyroid dysfunction or presence of thyroid goiter
  • Positivity of antibodies to thyroperoxidase (anti TPO).
  • Type 1 diabetes mellitus and / or other autoimmune disorders.
  • History of miscarriage or preterm labor.
  • History of radiation therapy with irradiation to the head or neck.
  • Severe obesity with body mass index (BMI) greater than 40 kg / m2.
  • Use of drugs such as amiodarone or lithium
  • Recent administration of iodinated contrast medium.
  • Residence in an area known to have moderate to severe iodine deficiency.

The feedback from High TSH in pregnancy should always be investigated: the most frequent cause of high TSH in pregnancy is the Hashimoto's thyroiditis.

The TSH values to define a hypothyroidism during gestation are:

Full-blown hypothyroidism in pregnancy:

  1. TSH greater than or equal to 2.5 mIU / L with reduced FT4; or
  2. a TSH greater than or equal to 10 mIU / L with any FT4.

Subclinical hypothyroidism in pregnancy:

TSH between 2.5 and 10 mIU / L with normal FT4 concentration.

In case of overt hypothyroidism during the pregnancy, there's a increased risk of: preterm birth, low weight and delayed neurocognitive development of the child at birth and above all increased risk of miscarriage (60% of spontaneous abortions in severe untreated hypothyroidism). It also increases the frequency of arterial hypertension for the mother. There replacement therapy with levothyroxine it is highly recommended to reduce the incidence of all these complications.

In case there is only subclinical hypothyroidism during the pregnancy, an increased risk of complications has been noted in women with anti-thyroperoxidase (anti-tpo) antibodies. Replacement therapy should be considered in this case.

Please note: for the women who were already in replacement therapy with levothyroxine, the dose should be increased during pregnancy, usually by 30% in autoimmune hypothyroidism and by 50% in people with hypothyroidism after partial or total removal of the thyroid (partial or total thyroidectomy).

High TSH symptoms

As already mentioned, high TSH is often not accompanied by particular symptoms, especially if the thyroid hormones are still normal, as in the case ofsubclinical hypothyroidism. In the phase of overt hypothyroidism, however, high TSH is associated with a condition of low fT3 and fT4, which may manifest itself with various signs and symptoms.

Symptoms of High TSH and Low Thyroid Hormones.

So what are the main ones symptoms of high TSH and low fT3 fT4 (hypothyroidism)?

The symptoms of high TSH are:

  • Less tolerance to cold
  • Mood instability and tendency to depression
  • Fatigue
  • Weight gain
  • Dry and fragile skin
  • Loss of eyebrows (especially the outer part)
  • Finer and more fragile nails
  • Constipation (constipation)
  • Carpal tunnel syndrome,
  • Irregularity of the menstrual cycle,
  • Increase of cholesterol,
  • Memory loss.

In other, less frequent cases, when the High TSH is associated with high levels of thyroid hormones, we will have the classic symptoms hyperthyroidism, related to the increased dose of circulating thyroxine and triiodothyronine.

Symptoms of high TSH and elevated thyroid hormones

What are the main ones symptoms of high TSH with high fT3 fT4? 

In this case, the symptoms of high TSH are:

    • Palpitations
    • Tachycardia
    • Agitation and anxiety
    • Nervousness and irritability
    • Tremor, especially in the hands
    • Alopecia
    • Alterations at the menstrual level
    • Diarrhea
    • Presence of exophthalmos
    • Possible presence of eyelid swelling
    • Sweats
    • Slimming
    • itch
    • Hot flashes

How the exam is carried out

The examination is carried out starting from a blood sample obtained with a venous sampling. It is not necessary to fast before the exam. As some medications can interfere with TSH measurement, you should warn your doctor about all ongoing drug therapy.

Factors affecting the measurement

What Factors Affect TSH Dosage?Hemolysis chance of the blood sample.

Daily changes in blood TSH levels: the highest levels are found around 10 pm, while basal levels are measurable at 10 am.

Recent radioactive iodine therapy.

Many drug therapies they can alter the TSH measurement. The following are the drugs that can most commonly raise TSH levels on blood tests:

    • methimazole
    • amiodarone,
    • lithium,
    • metoclopramide,
    • morphine,
    • clomiphene,
    • sodium nitroprusside,
    • propylthiouracil,
    • amphetamines,
    • phenylbutazone,
    • potassium iodide,
    • iodized radiographic contrast medium,
    • sulfonamides,
    • oral antidiabetics such as sulfonylureas,
    • intravenous administration of TRH (thyroid-releasing hormone)

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75 Comments
  1. ida maria marshall 2 years ago

    good afternoon I have withdrawn the answer of the analyzes x the thyroid of which the values are thyrotropin (tsh) 5.59 free thyroxine (ft4) I have to worry

    • Author
      Testlevels 2 years ago

      5.59 referred to thyroxine or tsh?

  2. Giuseppe Paglialunga 3 years ago

    Hello, I would like to submit the following values to you: tsh = 5.94 (0.40-4.00) ft3 = 2.75 (2-4) ft4 = 1.34 (0.50_2.50). I have ongoing prostatitis and urethritis and I have taken several antibiotics, last 10 ampoules of Rocefin 1 gram. Could the increase in TSH have affected this drug intake? Nonetheless, it is a time of great stress. And in any case what do you recommend?

  3. Anna Balestra 3 years ago

    Hi, my sister withdrew exams yesterday, waiting for the doctor I ask
    advice: TSH 4.89 (0.27-4.20) FT3 2.92 (2.00-4.40) FT4 0.94 (0.90-1.70) can this already be causing depression?
    Thank you and greetings

    • Author
      Testlevels 3 years ago

      Hi, the values of thyroid hormones are normal so, even with all the limitations related to not having visited the person concerned, this is not likely the cause of the depression. However, have everything evaluated by your doctor, best regards.

  4. Anna 3 years ago

    Hi! I was diagnosed with mild hyperthyroidism. The endocrinologist found my tsh and t3 to be slightly high. Unfortunately I don't remember the reference values of t3, but that of tsh (reference value 4.4. Value found 4.52). The doctor does not explain why the tsh is high since ilnon t3 is high. I did the thyroid ultrasound. The result: finely inhomogeneous thyroid structure with pseudonodular areas. Nothing important. Soon I will be doing the hormone tests again and magnetic resonance to see if there is any problem with the pituitary gland. I have read tsh secreted adenomas. It's dangerous? How.symptoms I have tachycardia, dizziness, sometimes skin rashes and stomach ache. The main problem is strong anxiety and sudden sadness. The doctor also assumes that there was an error in the analyzes. One more thing, what do you advise me to eat? And if I can exercise normally. Thanks

    • Testlevels 3 years ago

      It seems to me that the tests prescribed are correct, the symptoms could be related to the thyroid hormone imbalance, wait for the MRI scan and rely on the care of your trusted endocrinologist.

  5. GIUSEPPE 3 years ago

    These are the values of the exams: Tsh 4.16 (reference 0.40-4.00) FT3 1.45 (reference 2.00-4.00) FT4 0.92 (reference 0.50-2.50). They then recommended ultrasound with the following report: Thyroid in place, of shape and size within the limits, with a finely inhomogeneous echostructure but free from focal lesions of a solid or liquid type bilaterally. Periodic clinical-instrumental checks. After 4 months I took the exams again, with this result: TSH 4.40. FT3. 2.62. FT4. 1.06 (The references are the same as before). What do you advise me to do, do I need medication or something?

    • Testlevels 3 years ago

      I think that the endocrinologist specialist or your GP will advise you to continue with periodic checks of thyroid function, without additional therapies. Always refer to them in any case, best regards

    • GIUSEPPE 3 years ago

      Dear Doctors, I redid exams after 1 month with these results: TSH 5.94 (0.40 _ 4.00) _ FT3 2.75 (2 - 4) - FT4 1.34 (0.50 - 2.50) . I understand that I have ongoing prostatitis and urethritis and I have taken several antibiotics (CIPROCIN - LEVOXACINA for 20 days and also ROCEFIN for another 10 days. I would kindly like to know if these factors have affected the tsh value being also very anxious and stressed. I just have to keep monitoring the values or take some medication. Thanks

      • Author
        Testlevels 3 years ago

        The values must be checked again, however, refer to the attending physician who will be able to indicate the most appropriate tests.

  6. Angelica 3 years ago

    I have the tsh at 5.7 the right f3 f4 I'm taking a pill I always have anxiety is it due to that ??

    • Testlevels 3 years ago

      Hard to say, it is a subclinical hypothyroidism with normal levels of thyroid hormones.

  7. Sara 4 years ago

    Tsh 11.120
    Ft4 9.58
    Ft3 3.13. Treated with tirosint 6 drops ...

    • Testlevels 4 years ago

      hi, You probably need to adjust the therapy by slightly increasing the dose. In any case, before making any changes, always consult your doctor, best regards

  8. Danilo 4 years ago

    Good morning, my wife has done and repeated the usual exams, the values are somewhat alarming:
    TSH 55.26 mcIU / ml
    FT4 7.00 pmol / l
    TPO-Ab 236.00 IU / ml
    AbTg 0.10 IU / ml
    I'd say we're worried.

    • Testlevels 4 years ago

      Hi, this is probably an autoimmune hypothyroidism. Show the tests to your doctor who will show you the most appropriate information and therapy. Best regards

  9. Greta 4 years ago

    S.th reflex at 1.30 what does it mean?

    • Testlevels 4 years ago

      It means a normal TSH value

  10. Emanuela 4 years ago

    Good evening
    This morning I had a blood test for the thyroid the result was this

    Reflex thyrotropin (TSH) with possible dosage of FT4 and FT3
    Result 1,842 reference values 0.250-4.500

    • Testlevels 4 years ago

      Hi, this is normal, let your doctor see the report. Best regards

  11. Clementine 4 years ago

    Good morning ,
    A tip for exams withdrawn today recommended care EUTIROX 25MCG?
    TSH 4,670 (3.60-3.740)
    FT4 0.760 (0.76-1.46)

    SIDEREMIA 24 (40-150)
    HEMOGLOBIN 11.1 (12.0–16.0)
    Thanks

  12. tamy 4 years ago

    hi, I did the analyzes and the results were:
    TSH 4.06 (0.27-4.20)
    FT3 2.97 (2.02-4.43)
    FT4 13.16 (9.32-17.09)
    six months ago they were almost the half they were increasing every 6 months, and my doctor prescribed me eutirox 50 that i am taking, now i should repeat the tests after 4 months, but eutirox will make me stop I always take it, thanks?

  13. anna 4 years ago

    TSH reflex I withdrew my analyzes and in September the values were Ft3 2.4 (2.3-4.2) -Ft4 12.1 (8.0-18.0) -The TSH reflex with asterisk 20.10 (0 35-4.50). In this period I was taking eutirox 100. After that I switched to eutirox 75, under the advice of the doctor. After 4 months I did the analyzes again and the values were: Ft3-2.6 (2.3 -4.2) FT4-12.6 (8, O-18.0) TSH Reflex 10.24 (0.35-4.50) with asterisk Do I need to increase the dose of eutirox again?

  14. Lina 4 years ago

    Hi everyone, for about 9 years I have been suffering from hypothyroidism which I monitor regularly every 6 months by doing the necessary analyzes. Last week I withdrew the analyzes since I will have the visit from the endocrinilogue on March 18th. An altered value was found as regards tsh, while ft3 and ft4 were normal. The value of the tsh is 4.94. I regularly take 0.50 mg eutitox 4 times a week and 0.75 mg 3 times. Is this a normal value? Should I increase the doses? For 2 weeks now I have been feeling very tired, exhausted and I have difficulty even getting up in the morning. Sleepy and body aches. Could there be a link with the altered values? Thank you in advance .

  15. Asia 4 years ago

    Hi, doing the thyroid tests, the values of the trimester pregnancy appeared next to me. Should I worry?

    • Testlevels 4 years ago

      Don't worry it's the standard lab format. Best regards

  16. Anna Sarnacchiaro 4 years ago

    While doing the analyzes I also had a thyroid check introduced and the tsh is 4.390 I am worried. Could you answer me? Thank you very much. I am 71 years old.

    • Testlevels 4 years ago

      He must also measure the thyroid hormones. Best regards

  17. STEPHEN 4 years ago

    Good morning, exams:
    Tsh: 4.79
    ft4: 0.98
    Are these values worrying?

    • Testlevels 4 years ago

      Hi, The TSH is a little increased, the FT4 lacks the unit of measurement but it should be within the normal limits. Check for anti-thyroid antibodies. Show everything to your doctor, please, best regards

  18. Valentyna 4 years ago

    Hi, for years I have been treating thyroid gland I have withdrawn exams S-TSH 2,8ng / L, Ft4- 8.3 and TSH-31,267uUl / ml I take Internships 125 and little. Thanks

    • Testlevels 4 years ago

      The units of measurement are not clear, you report two measurements of TSH

      • Giulia 4 years ago

        Hi, I just ran blood tests.
        Tsh 4.07 (0.27 / 4.20)
        FT4 14.8 (12.0 / 22.0)
        Ant peroxidase 9 (<34)
        Anti-thyroglobulin 397 (<115)

        What can it be? I have cases of non-autoimmune hypothyroidism in my family. Thanks

        • Testlevels 4 years ago

          Thyroid hormones are normal, the slight rise in thyroglobulin antibodies is not significant, you will need to have periodic TSH and fT4 checks. Show everything to your doctor, best regards

  19. Carmen 4 years ago

    Hello ... I am a girl who has entered the fourth month of pregnancy ... two weeks ago the gynecologist prescribed me analysis tsh 5.950 (0.270-4.200) fy4 1.1 (0.93-1.70) ... yesterday she prescribed me 75g autirox therapy ... I wonder if I should worry about damage to the fetus ... Since I have never had thyroid tests and the problem is perhaps not only during the pregnancy period? Furthermore, will I have to take these drugs for life once therapy is started or could the thyroid gland work on its own? Thank you very much

    • Testlevels 4 years ago

      Hi, promptly initiated therapy should ensure absolutely normal fetal growth. Regarding the second question, it is not certain that everything evolves into hypothyroidism, it is essential to also check the anti-thyroid antibodies and redo the dosage of tsh and ft4 shortly. However, you can rely on the attending physician who will confirm the best diagnostic and therapeutic procedure. Best regards

  20. Sara Maffei 4 years ago

    Good morning,
    among the various blood tests, I performed for the first time that of the thyroid, which resulted:

    TSH 4.11 (reference values 0.30 - 3.94)

    Kindly, can you tell me if it is a worrying value?

    Thank you very much kind regards.

    • Testlevels 4 years ago

      Hi, no it's not a worrying value. Thyroid hormones?

    • Sara Maffei 4 years ago

      It's the only thyroid value I have, I think I'll have to do further tests to see the thyroid hormones.

      Thanks anyway for the feedback!

      Good evening!

  21. Joseph 4 years ago

    Good evening I am a 45 year old boy I did some tests because I suffer from hypothyroidism and I have the tsh at 13,000 I am very bad, give me some advice doctor, thanks.

    • Testlevels 4 years ago

      Hi, I advise you to contact your doctor and schedule an endocrinological visit to clarify the nature of the elevated Tsh. Thyroid hormones?

  22. Antonella 5 years ago

    Sn went to the doctor gave me to do the ultrasound to the head and the neck is the VES things

  23. Antonella 5 years ago

    Hi..two years ago I underwent a total thyroidectomy due to different modules including a malignant one..since then I took eutirox from 125..And the tsh has always been normal..Now with the last check the value has risen to 10.65… what happens? PS TT THE OTHER VALUES ARE GOOD.

    • Testlevels 5 years ago

      Hi, TSH values can have sudden fluctuations, also due to the different absorption of thyroid hormone therapy which is influenced by many factors. Tell your doctor who, also based on the T3 and T4 values, will advise you whether to change the therapy with Eutirox or whether to simply repeat the TSH in a couple of weeks to check if it is still high. Best regards

  24. Antonella 5 years ago

    I am afraid of having something bad I can have a normal life but because the TSH is high and the right thyroxine

    • Testlevels 5 years ago

      It could be an initial subclinical hypothyroidism, nothing that cannot be corrected with possible therapy with Eutirox. Best regards

  25. Antonella 5 years ago

    Good evening, I did the blood tests and the TSH at 5.60 thyroxine 10.4 what do you recommend sn in anxiety

    • Testlevels 5 years ago

      Hi, it would also be important to search for anti-thyroid hormones. Don't be anxious. Most cases of elevated TSH are not worrying. Show the tests to your doctor, best regards.

  26. ORIETTA 5 years ago

    GOOD EVENING I HAVE JUST WITHDRAWN THE ANALYSIS WITH RESULT TSH 3.00 WITH REFERENCE VALUES BETWEEN 0.0 AND 0.02 FT4 11.00 WITH VALUES BETWEEN 8 20 AND FT3 4.1 WITH REFERENCE VALUES BETWEEN 2.2 AND 4.7 WHAT DOES IT MEAN? THANKS

    • Testlevels 5 years ago

      If the FT4 unit of measurement is pmol / L, they are normal tests. Let your doctor see the tests, best regards.

  27. Alberto omboni 5 years ago

    They can affect the thyroid the tavor taken for ten years I do not sleep anything since 1984 you have to do thyroid tests I can not detach the tavor what I have to do thanks under tavor in massive doses

  28. Francesca Ravagni 5 years ago

    Good evening I have withdrawn blood tests today and the TSH value is 5.38 (0.20-4.50) FT4 14.6 (12.0-22.0) FT3 5.2 5.2 (3.2-6.8) Being the TSH a little outside could it affect the search for a pregnancy? Thanks

    • Testlevels 5 years ago

      Hi, thyroid hormones are normal, so this shouldn't affect the search for pregnancy. Nevertheless, the presence of high tsh in a picture of subclinical hypothyroidism during pregnancy could bother the baby, therefore any therapy with levothyroxine should be evaluated in agreement with your gynecologist or an endocrinologist, if this picture were to be confirmed during pregnancy. . Always and in any case rely on your doctor. Best regards

  29. Mari 5 years ago

    Good evening, today I collected the blood tests the following sn values
    FT3 2.69
    FT4 0.60
    TSH 36,900
    you can give me clarification is a completely foreign thing to me

    • Testlevels 5 years ago

      Hi, given that the units of measurement are missing, the values of the analyzes reported by you show a picture of hypothyroidism with high tsh and low levels of thyroid hormones. Did you search for thyroid antibodies? Show the tests to your doctor or the endocrinologist you refer to. Best regards

  30. Giovanna 5 years ago

    Hi, I am a mother with a 20-year-old son with a thyroid discovered at 14 years of age he has stopped taking his pill for a year because I am convinced that a hormone-based pill is good for the thyroid but causes other ailments I made him do the tests i values tsh6514 I no longer know how to convince him to take back his pill. What should I do?

    • Testlevels 5 years ago

      Hi, the TSH values reported are very high, perhaps a comma is missing. Try to convince your son, please, possibly by letting him talk to other doctors. Best regards

  31. HELEN OF MYCELES 5 years ago

    your site is very interesting
    and also very clear to understand
    thanks

  32. Daniela 6 years ago

    hello, I am an isulin-dependent diabetic aged 7, now I am 52. for some years I have had vitiligo on the hands and in some parts of the face, but the tsh exams were always in place, the last ones as well as at a glycated hemogobin of 10, which is horrible, they show frightening thyroid values:
    S-Ft4 at 11.2
    S- RTSH at 7.494
    S- Tpo Ab anti thyroperoxidase> 1300
    the doctor says I have inflammation in my circulation which could lead to heart problems
    another that I have to do an endocrinological visit and an echo to the thyroid x suspected nodules and that thyroid problems are often associated with vitiligo, x path of the immune system which is painful ...
    in short, no one can tell me what I have ... .. can you give me info about it? 1000 thanks. Daniela

    • Daniela 6 years ago

      ps the symptoms of hypothyroidism I have them almost all ... ... but always even when I had normal tsh. Daniela

    • admin 6 years ago

      Dear Daniela, undoubtedly these tests indicate a picture of thyroid suffering, with frankly positive anti-thyroperoxidase antibodies, which suggests (but obviously it is only a hypothesis and as such it should be taken) a picture of hyperthyroidism in the course of thyroiditis in the initial phase ( Hashimoto's thyroiditis?). All this could be framed in a type 3 autoimmune polyglandular syndrome (PGA), which is a syndrome in which an inflammatory process linked to the presence of auto-immunity affects different organs. Trust what the endocrinologist will tell you and I recommend that you check your diabetes well

  33. Antinea Anna Aiazzi 6 years ago

    hi I did the blood tests for thyroid control I have TSH at 4.808 what does it mean ?? thanks

    • admin 6 years ago

      Hi, the exam you describe shows a TSH just above the normal high limit. Ft3 and fT4?

  34. Iamina 6 years ago

    Good evening I have always had the tsh a little above the maximum limit and for this reason I took eutirox from 25, I continued like this for the whole pregnancy ... until the 38th week of gestation where the level had risen and they increased the dose to 50. I continued like this until 50 days after giving birth that by doing the exams the tsh dropped to 0.02 I went back to 25 eutirox tsh redone I had 0.03… ..from them I redone the tsh after a month I had it at 12.3…. .What's happening to me? Is tsh with these changes normal?

    • admin 6 years ago

      In pregnancy, as you know, there is a need to slightly increase the levothyroxine therapy (in her case Eutirox) and to keep the TSH at "normal-low" levels, that is normal but towards the low part of the normal range (to understand between 1.5 and 0.5 mIU / L). She probably returned to her normal needs after pregnancy and therefore the 50 µg of Eutirox was too much. Passing to 25 and then suspending the TSH has risen again to values above the norm. Rather, did you investigate why you need Levothyroxine therapy?

      • Iamina 6 years ago

        Good morning this week I have a visit to the endocrinologist and I hope he will give me some answers ... ... after having suspended it and that the value had returned to rise, I went back to taking dose 50, now I have redone the tests and the tsh and at 7.8 .......

        • admin 6 years ago

          Well the TSH is returning towards more appropriate values. The endocrinologist will tell you which dose of Eutirox is indicated.

        • Iamina 6 years ago

          As soon as I visit I'll let you know… .thank you. for answering me !!! Good day

  35. Francy 6 years ago

    High Tsh> 4
    t3 t4 in the standard

    These are the conditions what are the consequences in this case

    • admin 6 years ago

      From the values that you report the high TSH is placed in a picture of subclinical hypothyroidism (if you do not complain of symptoms): the thyroid produces a little less hormones than usual, the pituitary gland responds with increased TSH levels which bring thyroid hormones back to normal . There is therefore a somewhat "lazy" thyroid .. this is often linked to early stages of autoimmune, viral thyroiditis, or linked to the secondary effect of drugs. Often this degree remains stable (3/4 of the cases ten years later), sometimes it even regresses, other times it becomes full-blown hypothyroidism (with symptoms). Everything must be investigated with autoantibodies, ultrasound of the thyroid gland and specialist evaluation if possible .. in any case, contact your doctor.

  36. Vincenzo 6 years ago

    Good evening
    I am 50 years old
    14 years ago I underwent a total thyroidectomy
    I have been on Eutirox treatment since 175
    The latest tests performed worry me a little
    RESULT REFERENCE VALUES
    TSH 69 FROM 0.350 TO 5.500
    WHAT HAPPENS ME?

    • admin 6 years ago

      Hello, it's a high TSH, free thyroxine (fT4) how is it? showed it to your doctor?

    • HELEN OF MYCELES 5 years ago

      good morning, I'm Elena, I'm 52 and since I was 23 I have had a thyroid gland on the goiter which was analyzed with fine needle aspiration and a struma nodule was found. Today I received the TSH result and the result is 2.087 thyroid stimulating hormone and the free thyroxine is 0.84 I would like to know if everything is okay and if I am a hyper or hypo subject. i am always tired, sleepy, irritable, nervous etc, etc, what can i do? Thanks Elena

      • Testlevels 5 years ago

        From the tests she reports, TSH is normal and thyroxine releases at low normal values. This does not seem to be the reason for his nervousness and irritability. In any case, always refer to your doctor and / or the endocrinologist who follows you. Best regards.

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