Prik test - intradermal test

The Prik Test is an intradermal reaction test: it is a method for the routine diagnostics of allergies from inhalants, foods, drugs and insect poisons.

How does the Prok test work? this examination consists in the transport of a very small quantity of allergen beyond the basal layer of the epidermis where specific IgE adhering to mast cells are possibly present. For a quick screening, allergens in glycerosaline solution are used.


  • mite of the dust
  • grasses (mix)
  • parietary
  • mugwort
  • alternaria
  • cat dandruff


  • whole milk
  • beta-lactoglobulin
  • lactalbumin
  • egg white and olive red

Positive prick test

  • Histamine-like wheal with a diameter> 3 mm (Prick test) 6> 10 mm (intradermal test)

Negative prick test

  • Allergy not linked to specific IgE

False positives on the prick test

  • skin hyperreactivity
  • Presence of irritating or polluting substances in the extracts
  • Excessive concentration of the extracts
  • Excessive proximity to each other of positive skin tests
  • Possible accidental transport of allergens during execution

    False negatives during the prick test

  • Inactive extracts
  • Skin hyporeactivity: by age, presence of skin diseases, drug intake, or in case of refractoriness after intensely positive reactions)
  • After clinical manifestations recently disappeared
  • Medicines (antihistamines, cortisones)

Please note: food tests they are not very reliable, so the results must be supported by further investigations (specific IgE dosage, provocation test).


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