The feedback from low triglycerides it is less common than high triglycerides. THE triglycerides I'm fatty substances used as an energy source and in cell metabolism. The main ones causes of low triglycerides they are usually a state of malnutrition or malnutrition, more rarely due to liver disease or endocrine diseases (thyroid disease). THE symptoms of high triglycerides are often linked to the underlying disease, reduced triglycerides are unlikely to directly cause symptoms.
Low triglycerides: what they are
THE triglycerides they come from two main sources: they are introduced with food and to a lesser extent produced in our liver. As for the triglycerides introduced with the diet, the digestion of lipids in the intestine breaks down the triglycerides into the fatty acids that compose them. And after being absorbed by the intestinal mucosa, they are recombined back into their initial form. Since blood has a watery composition, triglycerides are hardly soluble in it. Then, in order to be conveyed to all cells, they are "wrapped" in water-soluble protein shells called chylomicromes.
As for the triglycerides produced by the liver, these are synthesized from simple sugars. Even these other triglycerides in order to be transported by the blood must be incorporated in water-soluble proteins known as VLDL (very low density lipoprotein). VLDL and chylomicrons together form the total concentration of circulating triglycerides.
The presence of low triglycerides (hypotryglyceridemia) can be a sign that something is not working in our body or in our diet.
What are the triglyceride values considered too low? Here are the normal and elevated values of triglycerides, expressed in mg / dL (milligrams per deciliter)
- Normal triglycerides: 40-150 mg / dL
- Low triglycerides: less than 40 mg / dL
- Low triglycerides in children: less than 30 mg / dl
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Causes Low Triglycerides
The decrease in blood triglycerides can be linked to several causes:
- Malnutrition: insufficient intake of triglycerides and carbohydrates with the diet inevitably leads to a reduction in circulating triglycerides.
- Malnutrition: some diets (such as the veganism) puts you at high risk of hypotiglyceridemia, as it is really difficult for vegans to eat foods that have fat, such as dried fruit. This problem does not affect vegetarians, who can easily eat cheeses, dairy products and eggs that contain moderate amounts of cholesterol and triglycerides.
- Sport activity: sports people, who practice physical activity on a regular basis, generally have lower blood triglyceride levels.
- Intestinal malabsorption: people with intestinal malabsorption problems (celiac disease, short bowel syndrome, hyponetalipoproteinemia, abetalipoproteinemia, results of intestinal resections, lactose intolerance, outcomes of pancreatitis) may not absorb triglycerides properly, resulting in reduced blood levels .
- Pharmacological therapy: some drugs can interfere with the absorption or metabolism of triglycerides, obviously starting from hypoglycemic drugs such as statins, fibrates and omega3 acids, but also the birth control pill, niacin, also known as nicotinic acid or vitamin PP (Pellagra Preventis) and vitamin C.
- Hyperthyroidism: hyperthyroidism can be of two types. Hyperthyroidism primary, linked to an increased function of the thyroid gland with increased production of thyroid hormones thyroxine is triiodothyronine, and reduced production of thyrotropin (Low TSH). Secondary hyperthyroidism is linked to an exaggerated production of thyroid stimulating hormone (with High TSH) by the pituitary and consequent increase in fT3 and fT4. In both cases, the increased metabolism generated by the high concentrations of thyroid hormones causes a reduction in circulating fats, with low triglycerides and cholesterol bass.
- Hepatopathies: the presence of liver problems, the main site of triglycerides production from carbohydrates (sugars), can cause the presence of reduced levels of triglycerides in the circulation. This is most evident in advanced liver disease, such as decompensated cirrhosis.
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Low triglycerides symptoms
What are the symptoms of low triglycerides? A condition of reduced triglycerides or hypotiglyceridemia may have symptoms related to the underlying condition that led to the drop in triglycerides.
Here are the main symptoms in low triglyceride situations.
- Symptoms related to malnutrition or malnutrition: asthenia (tiredness, weakness), headache, malaise, thinness, hair loss.
- Symptoms related to malabsorption: weight loss, diarrhea, steatorrhea (fatty stools), flatulence, abdominal pain (stomach pain).
- Symptoms related to hyperthyroidism: weight loss, dry skin, nervousness, diarrhea, anxiety, difficulty falling asleep, tremors, tachycardia.
- Symptoms related to liver disease: weight loss, accumulation of fluid in the legs and abdomen (edema and ascites), yellow skin (jaundice), itching.
Low triglycerides what to do
When triglycerides drop below the considered normal level, i.e. they are below 40 milligrams per deciliter, you are in the condition of hypotryglyceridemia.
So how to behave in case of hypotriglyceridemia?
What to do then in case of low triglycerides:
- Get blood tests to better investigate the nature of the decrease in triglycerides. The basic analyzes are blood count complete with hemoglobin, MCV, leukocyte and platelet counts, analysis of renal function (urea, creatinine, sodium, potassium), liver function (AST, ALT, GGT, ALP, total bilirubin and direct bilirubin and indirect bilirubin), lipid structure : total cholesterol, HDL cholesterol and LDL cholesterol, homocysteine, Lipoprotein a, thyroid function (TSH, free thyroxine and free triiodothyronine), anti-transglutaminase antibodies (aimed at the diagnosis of celiac disease).
- Change your diet, increasing the intake of foods containing fat and ensuring an adequate caloric intake (at least 1500 Kcal per day).
Tags: Laboratory medicine Blood